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REDUCING THE RISK FACTORS/TACKLING CHOLESTEROL:SUMMARIZING THE TRIALS
April 2, 2009
All the trials aiming to reduce the heart attack rate by lowering cholesterol levels have met with some success, but in most the success has been less spectacular than expected. The limitations have been partly caused by the design of the trials, that is, the control groups have often taken to healthier lifestyles as the news of the good effects started to spread.
A main problem with the cholesterol-lowering trials, however, has been their concentration on cholesterol only, and not on all the circumstances that contribute to heart attacks, such as high blood pressure, obesity, lack of exercise, smoking, and alcohol. In any doctor/patient discussion, all the risks would be put before the patient, and then doctor and patient would work together to reduce or abolish them. This was deliberately not done in many of the trials, as their aim was specifically to measure the effect of cholesterol lowering.
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